HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Carboxyphenylboronic Acid → 4'-[(R)-2-(Methoxy-methyl-carbamoyl)-1-o-tolyl-ethyl]-biphenyl-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Carboxyphenylboronic Acid | HCID 312183 | — |
| Reactant | (R)-3-(4-Bromophenyl)-N-methoxy-N-methyl-3-o-tolylpropanamide | HCID 71813344 | — |
| Product | 4'-[(R)-2-(Methoxy-methyl-carbamoyl)-1-o-tolyl-ethyl]-biphenyl-4-carboxylic acid | HCID 86661008 | — |
Reaction Steps
In analogy to example 74, step 6, from (R)-3-(4-bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide (example 142, step 1) and 4-boronobenzoic acid was prepared the title compound as a light brown foam, MS (ESI+): m/z=404.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-cb193427e1494976b2f35e5123b99343 |
| Source note | uspto-grants-2014_07 |