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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617866Generated: October 31, 2026

Methyl iodide → HCID 66668501, compound

https://huagongshe.com/reaction/1617866

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 66668328HCID 66668328—
ProductHCID 66668501HCID 66668501—

Reaction Steps

In analogy to example 161, step 1, (E)-5-(3-(4-chloro-2-fluorophenyl)acryloyl)pyridin-2(1H)-one was reacted with iodomethane in the presence of potassium carbonate to give the title compound as a yellow solid, MS (ESI+): m/z=292.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-b961689a6c08485aa3886ec0807ea34d
Source noteuspto-grants-2014_07