HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (E)-5-(3-(2,5-dichlorophenyl)acryloyl)pyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 66666230 | HCID 66666230 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (E)-5-(3-(2,5-dichlorophenyl)acryloyl)pyridin-2(1H)-one | HCID 66668831 | — |
Reaction Steps
In analogy to example 162, step 2, (E)-3-(2,5-dichlorophenyl)-1-(6-methoxypyridin-3-yl)prop-2-en-1-one was reacted with concentrated aqueous HCl in 1,4-dioxane to give the title compound as a light yellow solid, MS (ESI+): m/z=294.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-6c102a0e6b2a49f68409949f25e1e898 |
| Source note | uspto-grants-2014_07 |