Hydroxyamine hydrochloride → HCID 58043604, compound

Participants

Reaction Steps

In analogy to example 151, step 3, 5-{3-(4-chloro-2-methyl-phenyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-propionyl}-1-methyl-1H-pyridin-2-one was reacted with hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate to give the title compound containing less than 10% of the corresponding Z isomer as a colourless solid, MS (ESI+): m/z=464.2 [M+H]+.

Provenance & Evidence