Hydroxyamine hydrochloride → HCID 136167065, compound

Participants

Reaction Steps

In analogy to example 132, step 6, from (R)-3-(4-bromophenyl)-3-(4-chloro-2-methyl-phenyl)-1-(2-(hydroxymethyl)pyridin-4-yl)propan-1-one (example 282, step 1) and hydroxyl-amine hydrochloride in the presence of sodium hydrogencarbonate was prepared the title compound as a white foam, MS (ESI+): m/z=459.2 ([M+H]+).

Provenance & Evidence