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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1618057Generated: November 2, 2026

Hydroxyamine hydrochloride → HCID 136167059, compound

https://huagongshe.com/reaction/1618057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 66667137HCID 66667137—
ProductHCID 136167059HCID 136167059—

Reaction Steps

In analogy to example 132, step 6, from (R)-3-(4-(1-acetylpiperidin-4-yl)phenyl)-3-(4-chloro-2-methylphenyl)-1-(2-methylpyridin-4-yl)propan-1-one and hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate was prepared the title compound as a white foam, MS (ESI+): m/z=490.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-441422470eaa46cc8b79aac85aba2443
Source noteuspto-grants-2014_07