反应详情

Prepared according to procedure K using 6′-bromo-2,3,5,6-tetrahydrospiro[pyran-4,3′-pyrrolo[3,2-b]pyridin]-2′(1′H)-one (138 mg, 0.487 mmol) and sodium bis(2-methoxyethoxy)aluminium hydride (304 μL, 1.560 mmol) in toluene (3 mL). After purification 6′-bromo-1′,2,2′,3,5,6-hexahydrospiro[pyran-4,3′-pyrrolo[3,2-b]pyridine] was obtained as a white solid.

1. customPrepared
2. customAfter purification 6′-bromo-1′,2,2′,3,5,6-hexahydrospiro[pyran-4,3′-pyrrolo[3,2-b]pyridine]
3. customwas obtained as a white solid