HCID 59631474, compound → HCID 59631171, compound

HRID 1618569Notes

Reaction equation

HRID 1618569 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:18])=[C:6]([NH:8][C:9](=[O:17])[CH:10]([CH3:16])[C:11]([O:13]CC)=[O:12])[CH:7]=1>C1COCC1>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:18])=[C:6]([NH:8][C:9](=[O:17])[CH:10]([CH3:16])[C:11]([OH:13])=[O:12])[CH:7]=1

Participants

3

Reactant 1

HCID 59631474HCID 59631474, compound

Product 1

HCID 59631171HCID 59631171, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The acid was prepared according to procedure B using ethyl 3-(5-fluoro-2-methylphenylamino)-2-methyl-3-oxopropanoate (2.45 g, 9.67 mmol) in THF (9.67 mL). The crude product was used without further purification. Mass Spectrum (ESI) m/e=226.0, (M+1).

Workup

  1. customThe acid was prepared
  2. customThe crude product was used without further purification

Sources & evidence

ORD record
ord-535f9563fdad4d80a27012b98fc4f585
Source dataset
uspto-grants-2014_07
Patent number
US08765940B2

Reaction notes

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