Ethyl 2-methylacetoacetate → HCID 178432160, compound

HRID 1618587Notes

Reaction equation

HRID 1618587 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[CH3:9][CH:10]([C:16](=O)[CH3:17])[C:11](OCC)=[O:12]>>[Cl:1][C:2]1[CH:8]=[C:7]2[C:5](=[CH:4][CH:3]=1)[N:6]=[C:16]([CH3:17])[C:10]([CH3:9])=[C:11]2[OH:12]

Participants

3

Reactant 2

HCID 701Ethyl 2-methylacetoacetateHCID 78124-Chloroaniline

Product 1

HCID 178432160HCID 178432160, compound

Procedure

Prepared according to procedure R using 4-chloroaniline (2 g, 15.68 mmol) and ethyl 2-methyl-3-oxobutanoate (4.53 mL, 31.36 mol) to give 6-chloro-2,3-dimethylquinolin-4-ol as a white solid: Mass Spectrum (ESI) m/e=208.0 (M+1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-948468e31673465089063ec5f388154a
Source dataset
uspto-grants-2014_07
Patent number
US08765940B2

Reaction notes

Loading…