反应详情

Prepared according to procedure E using 2,4-dichloro-3-methyl-1,7-naphthyridine (100 mg, 0.469 mmol), 4-methyl-2-(tributylstannyl)pyridine (215 mg, 0.563 mmol) and Pd(PPh3)4 (54.2 mg, 0.047 mmol). After purification 4-chloro-3-methyl-2-(4-methylpyridin-2-yl)-1,7-naphthyridine was obtained as a white solid. Mass Spectrum (ESI) m/e=270.0 (M+1).

1. customPrepared
2. customAfter purification 4-chloro-3-methyl-2-(4-methylpyridin-2-yl)-1,7-naphthyridine
3. customwas obtained as a white solid