反应详情

18 g of 1,3,5-tris(4-hydroxyphenyl)benzene was dissolved in 500 ml of tetrahydrofuran. 6 g of potassium t-butoxide was added and the mixture was stirred at room temperature for five minutes. After the addition of 10 g of bromo-t-butylacetate dropwise, the mixture was stirred for six hours while heating at 60° C. After evaporating tetrahydrofuran under reduced-pressure, the reaction product was extracted with 300 ml of dichloromethane, purified using a silica gel column, and dried to obtain 4.6 g of 1-(t-butoxycarbonylmethoxyphenyl)-3,5-di(4-hydroxyphenyl)benzene.

1. stirringthe mixture was stirred for six hours
2. temperaturewhile heating at 60° C
3. customAfter evaporating tetrahydrofuran under reduced-pressure
4. extractionthe reaction product was extracted with 300 ml of dichloromethane
5. custompurified
6. customdried