HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethynyl-3-fluorobenzene → HCID 136038173, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethynyl-3-fluorobenzene | HCID 520218 | — |
| Reactant | 7-Bromo-3,4-dihydroquinazolin-4-one | HCID 135555612 | — |
| Product | HCID 136038173 | HCID 136038173 | — |
Reaction Steps
The title compound was prepared from 7-bromoquinazolin-4(3H)-one and 1-ethynyl-3-fluorobenzene according to the experimental procedure as described in Example 1.1. MS (ESI): 265 (MH+); 1H NMR (300 MHz, DMSO-d6) δ 12.37 (s, 1H), 8.14 (s, 2H), 7.83 (s, 1H), 7.68-7.64 (m, 1H), 7.53-7.49 (m, 3H), 7.36-7.33 (m, 1H). mGluR5 PAM EC50: +.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772301B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-e3a0c284051d415191e8171a247f93ce |
| Source note | uspto-grants-2014_07 |