HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromobutane → HCID 58574575, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromobutane | HCID 6554 | — |
| Reactant | HCID 58574180 | HCID 58574180 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58574575 | HCID 58574575 | — |
Reaction Steps
A solution of 9-bromo-3,4-dihydro-1H-pyrazino[2,1-b]quinazolin-6(2H)-one (30 mg, 0.11 mmol) and excess 2-bromobutane in DMF (5 mL) was stirred at 140° C. for 6 h. Then the reaction mixture was concentrated and purified by column chromatography to give the desired product. MS (ESI): 336, 338 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772301B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-c1d3517650bf49e6846dd5c7847ed9e2 |
| Source note | uspto-grants-2014_07 |