HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(1-amino-2-methylpropan-2-ylamino)acetate → 5,5-Dimethylpiperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(1-amino-2-methylpropan-2-ylamino)acetate | HCID 58574370 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5,5-Dimethylpiperazin-2-one | HCID 23319655 | — |
Reaction Steps
A solution of ethyl 2-(1-amino-2-methylpropan-2-ylamino)acetate (0.8 g, 4.7 mmol) in DMF (20 mL) was stirred at reflux for 1 h. After it was cooled to room temperature, the mixture was concentrated to give the crude product, which was directly used for the next step. MS (ESI): 129 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772301B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-93d3cf467db04cf9a0201c04cb14507c |
| Source note | uspto-grants-2014_07 |