Ethyl 3-(1-Boc-2-pyrrolidinyl)acrylate → HCID 58574582, compound

Participants

Reaction Steps

A solution of tert-butyl 2-(3-ethoxy-3-oxoprop-1-enyl)pyrrolidine-1-carboxylate (4 g, 14.9 mmol) and Pd/C (1 g, 10% weight) in MeOH was stirred at room temperature. Hydrogen from a balloon was ventilated to the suspension continuously and the completion of the reaction was monitored by TLC. After the suspension was filtered, the organic phases was concentrated to give the desired product, which was directly used for the next step without further purification. MS (ESI): 272 (MH+).

Provenance & Evidence