反应详情

A solution of 4-bromo-2-carboxymethyl-benzoic acid (200 mg, 1.1 mmol) in 2 mL acetic anhydride was refluxed for 10 h. Then the mixture was concentrated to dryness and the crude 6-bromoisochroman-1,3-dione was used into the next step without further purification.

1. concentrationThen the mixture was concentrated to dryness
2. customthe crude 6-bromoisochroman-1,3-dione was used into the next step without further purification