HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-(carboxymethyl)benzoic acid → 6-Bromoisochroman-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-(carboxymethyl)benzoic acid | HCID 53440132 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 6-Bromoisochroman-1,3-dione | HCID 21782486 | — |
Reaction Steps
A solution of 4-bromo-2-carboxymethyl-benzoic acid (200 mg, 1.1 mmol) in 2 mL acetic anhydride was refluxed for 10 h. Then the mixture was concentrated to dryness and the crude 6-bromoisochroman-1,3-dione was used into the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772301B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-2b197f55248443d384a2191fd12cdeb9 |
| Source note | uspto-grants-2014_07 |