反应详情

温度

30 °C

To a suspension of 10% Pd/C (85 mg) in methanol was added a solution of 5-(4-(benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxane (850.0 gm, 0.00775 moles) in methanol (20 ml). To this was added ammonium formate (900 mg, 0.0143 mole) and the reaction mixture was refluxed for 2 hrs. The reaction mixture was then cooled to 30° C. and filtered through celite. The filtrate was evaporated under reduced pressure and residue was dissolved in dichloromethane and filtered through celite. The filtrate was evaporated under reduced pressure to yield 600 mg product as white solid.

1. temperaturethe reaction mixture was refluxed for 2 hrs
2. filtrationfiltered through celite
3. customThe filtrate was evaporated under reduced pressure and residue
4. dissolutionwas dissolved in dichloromethane
5. filtrationfiltered through celite
6. customThe filtrate was evaporated under reduced pressure