Cyanamide → HCID 178480887, compound

Participants

Reaction Steps

0.4 g I.21 (1-[2-(5-amino-1,3-dihydro-isoindol-2-yl)-ethyl]-3-methyl-imidazolidin-2-one hydrochloride) was added to a mixture of 0.37 g cyanamide in 3 ml dioxane and 1 ml 4 N hydrochloric acid in dioxane. The mixture was irradiated at 140° C. in a microwave for 30 min. The solvent was evaporated and the residue was used in the next step without purification.

Provenance & Evidence