HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+/-)-{3-Chloro-6-[(4-fluoro-benzenesulfonyl)-methyl-amino]-5,6,7,8-tetrahydro-2,4b-diaza-fluoren-9-yl}-acetic acid → HCID 59471427, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+/-)-{3-Chloro-6-[(4-fluoro-benzenesulfonyl)-methyl-amino]-5,6,7,8-tetrahydro-2,4b-diaza-fluoren-9-yl}-acetic acid | HCID 59471435 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59471427 | HCID 59471427 | — |
Reaction Steps
A solution of (±)-{3-chloro-6-[(4-fluoro-benzenesulfonyl)-methyl-amino]-5,6,7,8-tetrahydro-2,4b-diaza-fluoren-9-yl}-acetic acid (2 mg) and 2 mg of Pd/C (20%) in 0.5 mL of MeOH was stirred under Hz (balloon pressure) for 8 h. The suspension was filtered through celite and the filtrate was concentrated to give the title compound. MS (ES): 418.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772312B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-7eb4671d6461496d98519a9149d9a41c |
| Source note | uspto-grants-2014_07 |