反应详情

3.00 g (8.79 mmol) 3-(4-benzylamino-3-hydroxy-benzoyl)-2-methyl-pentanoic acid, 6.31 mL (126.00 mmol) hydrazine hydrate and 25 mL glacial acetic acid are stirred for 3 h at 110° C. The reaction mixture is concentrated by rotary evaporation i. V. and the residue is separated through RP (xBridge, MeOH/H2O/TFA).

1. concentrationThe reaction mixture is concentrated by rotary evaporation i
2. customand the residue is separated through RP (xBridge, MeOH/H2O/TFA)