HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1619960Generated: November 2, 2026
Dimethylformamide → 2-Hydroxy-1-(2-phenyl-benzoxazol-6-yl)-butan-1-one
https://huagongshe.com/reaction/1619960
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 2-Bromo-1-(2-phenyl-benzoxazol-6-yl)-butan-1-one | HCID 86689065 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Hydroxy-1-(2-phenyl-benzoxazol-6-yl)-butan-1-one | HCID 67462776 | — |
Reaction Steps
200 mg (581 μmol) 2-bromo-1-(2-phenyl-benzoxazol-6-yl)-butan-1-one are combined with 1.2 ml DMF and 0.8 ml of water. The mixture is stirred for 3 h at 100° C. and then separated by RP-HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08772323B2 |
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| Source dataset | uspto-grants-2014_07 |
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| ORD ID | ord-e6240a30b7d64f7c91f09afb6e82a958 |
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| Source note | uspto-grants-2014_07 |
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