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HRID1619981

反应详情

EQUATION

反应方程式

HRID 1619981 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)O
HCID176

Acetic Acid

C2H4O2

结构：Cc1ccc(S(=O)(=O)O)cc1.O
HCID521998

4-Methylbenzenesulfonic acid hydrate

C7H10O4S

结构：CC1CC(=O)NN=C1c1ccc(NC(=O)c2ccc(C#N)cc2)c(O)c1
HCID67462621

未命名化合物

PRODUCTS

生成物

1
结构：CC1CC(=O)NN=C1c1ccc2nc(-c3ccc(C#N)cc3)oc2c1
HCID67461007

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

250 mg (718 μmol) 4-cyano-N-[2-hydroxy-4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-benzamide and 126 mg (718 μmol) para-toluenesulphonic acid monohydrate are refluxed with 10 ml glacial acetic acid for 3 h. Then the solv. is eliminated by rotary evaporation i.V., water is added to the residue and the product is filtered off.

WORKUP

后处理

  1. filtrationthe product is filtered off