HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-methoxybenzyl)hydrazine → 3-(4-Methoxy-benzyl)-3,4-diaza-bicyclo[4.1.0]heptan-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-methoxybenzyl)hydrazine | HCID 16194 | — |
| Reactant | 3-Oxabicyclo(3.1.0)hexane-2,4-dione | HCID 2734721 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-(4-Methoxy-benzyl)-3,4-diaza-bicyclo[4.1.0]heptan-2,5-dione | HCID 10776806 | — |
Reaction Steps
1.0 g (8.92 mmol) 1,2-cyclopropanedicarboxylic acid anhydride is dissolved in 5 ml acetonitrile, 1.5 g (9.86 mmol) 4-methoxy-benzyl-hydrazine dissolved in 5 ml acetonitrile are added dropwise and the mixture is refluxed overnight. During cooling to RT a precipitate is formed, which is filtered off, washed with acetonitrile and dried in the vacuum dryer at 50° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772323B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-579cbca122da45d592157a85c31868ed |
| Source note | uspto-grants-2014_07 |