HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86689078, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-{2-[4-(2,2-dimethoxy-1-methyl-ethoxy)-phenyl]-benzoxazol-6-yl}-5-ethyl-4,5-dihydro-2H-pyridazin-3-one | HCID 67467325 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86689078 | HCID 86689078 | — |
Reaction Steps
54 mg (74 μmol) 6-{2-[4-(2,2-dimethoxy-1-methyl-ethoxy)-phenyl]-benzoxazol-6-yl}-5-ethyl-4,5-dihydro-2H-pyridazin-3-one, 200 μL (4 mmol/mL; 800 μmol) HCl and 5 ml dioxane are stirred for 40 min at 80° C. Then the mixture is extracted with EA, extracted twice with H2O and then with sat. saline solution. The solv. of the org. phase is eliminated i.V.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772323B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-d1e9e5b572394133a32f5903bb9466be |
| Source note | uspto-grants-2014_07 |