HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620017Generated: November 2, 2026
5-methyl-6-(2-thiophen-2-yl-benzoxazol-6-yl)-4,5-dihydro-2H-pyridazin-3-one → 5-methyl-6-(2-thiophen-2-yl-benzoxazol-6-yl)-2H-pyridazin-3-one
https://huagongshe.com/reaction/1620017
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 5-methyl-6-(2-thiophen-2-yl-benzoxazol-6-yl)-4,5-dihydro-2H-pyridazin-3-one | HCID 67461228 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-methyl-6-(2-thiophen-2-yl-benzoxazol-6-yl)-2H-pyridazin-3-one | HCID 67462394 | — |
Reaction Steps
100 mg (321 μmol) 5-methyl-6-(2-thiophen-2-yl-benzoxazol-6-yl)-4,5-dihydro-2H-pyridazin-3-one, 0.08 mg (964 μmol) activated manganese(IV)oxide and 10 ml dioxane are combined and stirred overnight at 120° C. The reaction mixture is filtered through Celite, washed with DCM and EA and the solv. of the filtrate is eliminated i.V. The residue is recrystallised with DMF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08772323B2 |
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| Source dataset | uspto-grants-2014_07 |
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| ORD ID | ord-cc012d534f784aa091530b9e63683dbe |
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| Source note | uspto-grants-2014_07 |
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