Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620436Generated: October 31, 2026

(+-)-3-Quinuclidinol → Ethyl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

https://huagongshe.com/reaction/1620436

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-3-QuinuclidinolHCID 15381—
ReactantSolifenacinHCID 154059—
ProductEthyl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylateHCID 25178885—

Reaction Steps

This solution was taken for condensation reaction with (RS)-3-quinuclidinol in the next stage to prepare Solifenacin and its diastereomer.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772491B2
Source datasetuspto-grants-2014_07
ORD IDord-d59b003254474475b8c6d97a9f5ba6fb
Source noteuspto-grants-2014_07