1-Propanol, 3-amino-2,2-dimethyl- → HCID 178450595, compound

Participants

Reaction Steps

To a solution of 3-amino-2,2-dimethylpropan-1-ol (4.05 g) in ethanol (100 mL) was added 4-thioxo-1,3-thiazolidin-2-one (5.07 g). The reaction mixture was stirred at room temperature overnight, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (NH, ethyl acetate) to give the title compound (4.52 g).

Provenance & Evidence