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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620621Generated: October 29, 2026

4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178518112, compound

https://huagongshe.com/reaction/1620621

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Sulfanylidene-1,3-thiazolidin-2-oneHCID 1539595—
Reactant[4-(Aminomethyl)oxan-4-yl]methanolHCID 22379474—
SolventEthanolHCID 702—
ProductHCID 178518112HCID 17851811287.4%

Reaction Steps

To a solution of 4-thioxo-1,3-thiazolidin-2-one (898 mg) in ethanol (15 mL) was added a solution (5 mL) of [4-(aminomethyl)tetrahydro-2H-pyran-4-yl]methanol (1.00 g) in ethanol, and the mixture was heated under reflux overnight. The reaction mixture was cooled to room temperature, the precipitate was collected by filtration, and the obtained powder was washed with ethyl acetate to give the title compound (1.44 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772277B2
Source datasetuspto-grants-2014_07
ORD IDord-c71d08864ab348c58adc3c6f894f5dd1
Source noteuspto-grants-2014_07