HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178518112, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Sulfanylidene-1,3-thiazolidin-2-one | HCID 1539595 | — |
| Reactant | [4-(Aminomethyl)oxan-4-yl]methanol | HCID 22379474 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178518112 | HCID 178518112 | 87.4% |
Reaction Steps
To a solution of 4-thioxo-1,3-thiazolidin-2-one (898 mg) in ethanol (15 mL) was added a solution (5 mL) of [4-(aminomethyl)tetrahydro-2H-pyran-4-yl]methanol (1.00 g) in ethanol, and the mixture was heated under reflux overnight. The reaction mixture was cooled to room temperature, the precipitate was collected by filtration, and the obtained powder was washed with ethyl acetate to give the title compound (1.44 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772277B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-c71d08864ab348c58adc3c6f894f5dd1 |
| Source note | uspto-grants-2014_07 |