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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620650Generated: October 31, 2026

HCID 86678817, compound → HCID 86678816, compound

https://huagongshe.com/reaction/1620650

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86678817HCID 86678817—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
ProductHCID 86678816HCID 86678816104.3%

Reaction Steps

A solution of (R)-benzyl[1-(dimethylamino)-3-hydroxy-1-oxopropan-2-yl]carbamate (1.30 g) and 10% palladium carbon (130 mg) in methanol (30 mL) was stirred at room temperature for 7 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (673 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772277B2
Source datasetuspto-grants-2014_07
ORD IDord-d40d4c0d133e4d8699d273a2f6d7183e
Source noteuspto-grants-2014_07