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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620662Generated: November 3, 2026

4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178521297, compound

https://huagongshe.com/reaction/1620662

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Sulfanylidene-1,3-thiazolidin-2-oneHCID 1539595—
Reactant2-amino-N-cyclopropylacetamideHCID 4962727—
SolventEthanolHCID 702—
ProductHCID 178521297HCID 17852129788%

Reaction Steps

To a solution of N-cyclopropylglycinamide (1.22 g) (J. Med. Chem. 2005, 48, 7808-7820) in ethanol (12 mL) was added 4-thioxo-1,3-thiazolidin-2-one (1.42 g), and the mixture was stirred at room temperature for 5 hr. The precipitate was collected by filtration, and the solid was washed with ethanol to give the title compound (2.0 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772277B2
Source datasetuspto-grants-2014_07
ORD IDord-0b8204a8043e4a2d837411209ea78c16
Source noteuspto-grants-2014_07