HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178521297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Sulfanylidene-1,3-thiazolidin-2-one | HCID 1539595 | — |
| Reactant | 2-amino-N-cyclopropylacetamide | HCID 4962727 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178521297 | HCID 178521297 | 88% |
Reaction Steps
To a solution of N-cyclopropylglycinamide (1.22 g) (J. Med. Chem. 2005, 48, 7808-7820) in ethanol (12 mL) was added 4-thioxo-1,3-thiazolidin-2-one (1.42 g), and the mixture was stirred at room temperature for 5 hr. The precipitate was collected by filtration, and the solid was washed with ethanol to give the title compound (2.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772277B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-0b8204a8043e4a2d837411209ea78c16 |
| Source note | uspto-grants-2014_07 |