HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178456890, compound → HCID 86678852, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178456890 | HCID 178456890 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86678852 | HCID 86678852 | 31.7% |
Reaction Steps
A solution of 4-(prop-2-yn-1-ylamino)-1,3-thiazol-2(5H)-one (120 mg) in methanol (2 mL) was stirred at 140° C. for 1 hr under microwave irradiation, and the solvent was evaporated. The residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (38 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772277B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-9a7df66fcf844223ba2186450621ddbc |
| Source note | uspto-grants-2014_07 |