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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620692Generated: October 31, 2026

HCID 178456890, compound → HCID 86678852, compound

https://huagongshe.com/reaction/1620692

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178456890HCID 178456890—
SolventMethanolHCID 887—
ProductHCID 86678852HCID 8667885231.7%

Reaction Steps

A solution of 4-(prop-2-yn-1-ylamino)-1,3-thiazol-2(5H)-one (120 mg) in methanol (2 mL) was stirred at 140° C. for 1 hr under microwave irradiation, and the solvent was evaporated. The residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (38 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772277B2
Source datasetuspto-grants-2014_07
ORD IDord-9a7df66fcf844223ba2186450621ddbc
Source noteuspto-grants-2014_07