HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen chloride-ethyl acetate → HCID 178479699, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | HCID 178521294 | HCID 178521294 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178479699 | HCID 178479699 | — |
Reaction Steps
To a solution of N2-[(5Z)-5-({1-[2,4-bis(trifluoromethyl)benzyl]piperidin-4-yl}methylidene)-2-oxo-2,5-dihydro-1,3-thiazol-4-yl]-N-cyclopropylglycinamide (700 mg) in THF (10 mL) was added a solution of 4N hydrogen chloride/ethyl acetate (0.33 mL), and the precipitate was so collected by filtration to give the title compound (301 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772277B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-7cf296dc758d421cb7977cf9523b814c |
| Source note | uspto-grants-2014_07 |