HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86678926, compound → HCID 86678927, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86678926 | HCID 86678926 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86678927 | HCID 86678927 | 58.4% |
Reaction Steps
To a solution of benzyl[(1S)-2-(dimethylamino)-1-(1-hydroxycyclopropyl)-2-oxoethyl]carbamate (190 mg) in ethanol (5 mL) was added 10% palladium carbon (69 mg) at room temperature. The reaction mixture was stirred at room temperature for 5 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (60 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772277B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-a6aec1674a4342679378c216bd8f6d11 |
| Source note | uspto-grants-2014_07 |