4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178463636, compound

HRID 1620779Notes

Reaction equation

HRID 1620779 reaction equation
S=[C:2]1[CH2:6][S:5][C:4](=[O:7])[NH:3]1.C(O)C.[CH2:11]([NH2:13])[CH3:12]>C(O)C>[CH2:11]([NH:13][C:2]1[CH2:6][S:5][C:4](=[O:7])[N:3]=1)[CH3:12]

Participants

4

Reactant 2

HCID 15395954-Sulfanylidene-1,3-thiazolidin-2-oneHCID 22128961Ethanamine ethanol

Product 1

HCID 178463636HCID 178463636, compoundYield 46.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 4-thioxo-1,3-thiazolidin-2-one (640 mg) in ethanol (6 mL) was added 30% ethanamine ethanol solution (722 mg), and the mixture was stirred at room temperature for 3 hr. The reaction mixture was concentrated under reduced pressure, and the residue was washed with 2-propanol to give the title compound (320 mg).

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. washthe residue was washed with 2-propanol

Sources & evidence

ORD record
ord-47ca4d38006f46fdb020a1f1380f1e4c
Source dataset
uspto-grants-2014_07
Patent number
US08772277B2

Reaction notes

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