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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620886Generated: October 25, 2026

Potassium hydroxy sulfite → 4-{[5-(Methylsulfinyl)-1,3-thiazol-2-yl]carbamoyl}phenyl acetate

https://huagongshe.com/reaction/1620886

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium hydroxy sulfiteHCID 23707502—
Reactant4-{[5-(Methylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}phenyl acetateHCID 57571820—
SolventChloroformHCID 6212—
Product4-{[5-(Methylsulfinyl)-1,3-thiazol-2-yl]carbamoyl}phenyl acetateHCID 56969393—

Reaction Steps

Using the Oxone® procedure as described in section 1.5.1.7 for the synthesis of compound (I), 515 (0.841 g, 2.73 mmol) gives crude 7. The crude product is stirred with chloroform (50 mL) and the suspension is filtered. The pad is washed once with chloroform and air dried to give pure 7 (0.35 g) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772502B2
Source datasetuspto-grants-2014_07
ORD IDord-7e3ee9d730574924bdaf720001ab6ccb
Source noteuspto-grants-2014_07