HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium hydroxy sulfite → 4-{[5-(Methylsulfinyl)-1,3-thiazol-2-yl]carbamoyl}phenyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium hydroxy sulfite | HCID 23707502 | — |
| Reactant | 4-{[5-(Methylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}phenyl acetate | HCID 57571820 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-{[5-(Methylsulfinyl)-1,3-thiazol-2-yl]carbamoyl}phenyl acetate | HCID 56969393 | — |
Reaction Steps
Using the Oxone® procedure as described in section 1.5.1.7 for the synthesis of compound (I), 515 (0.841 g, 2.73 mmol) gives crude 7. The crude product is stirred with chloroform (50 mL) and the suspension is filtered. The pad is washed once with chloroform and air dried to give pure 7 (0.35 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772502B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-7e3ee9d730574924bdaf720001ab6ccb |
| Source note | uspto-grants-2014_07 |