Hydrochloric Acid → HCID 21758136, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of tert-butyl 2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethylcarbamate (831 mg, 2.76 mmol) in dioxane (5 mL) was added HCl in dioxane (4M, 6.89 mL, 27.6 mmol) dropwise. The reaction mixture was stirred at 20° C. for 1.5 h. The crude reaction mixture was concentrated in vacuo. Heptane was added and the suspension was stirred for 30 min and evaporated in vacuo to give the product as white solid (760 mg, 2.72 mmol, 98.5%). MS: M=202.3 (M−2HCl+H)+

Provenance & Evidence