Hydrochloric Acid → HCID 71279189, compound

Participants

Reaction Steps

A solution of 5-[2-bis(tert-butoxycarbonyl)aminoethyl]-1-benzyl-3-phenyl-[1,2,4]triazole (103 mg, 215 μmol) and tert-butyl 2-(1-benzyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethylcarbamate (38.5 mg, 102 μmol) in HCl (4M in Dioxane, 3 mL, 12.0 mmol) was stirred at RT for 1 h. The reaction mixture was concentrated in vacuo and the resulting solid was poured on diethyl ether (2.5 mL), filtrated off and washed with little diethyl ether. The obtained white crystals were dried (74 mg, 74%) and used without further purification for the next step.

Provenance & Evidence