Triphenylphosphine → HCID 71279235, compound

Participants

Reaction Steps

4-(2-Azidoethyl)-5-methyl-2-p-tolylthiazole (160 mg, 619 μmol), triphenylphosphine polymer bound (270 mg, 803 μmol) and water (2 drops, 8 μL, 444 μmol) were combined at RT to give a brown suspension. The mixture was stirred at RT overnight. The suspension was filtered and the liquid was evaporated to give the product as light yellow oil (151 mg, 617 μmol, 99.7%) which was used without further purification for the next step.

Provenance & Evidence