Phenylhydrazine → HCID 86677496, compound

HRID 1621164Notes

Reaction equation

HRID 1621164 reaction equation
[Cl:1][CH2:2][C:3](/[N:5]=[C:6](\OCC)/[C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[CH:8]=1)=O.[C:17]1([NH:23][NH2:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[Cl:1][CH2:2][C:3]1[N:23]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:24]=[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[CH:8]=2)[N:5]=1

Participants

3

Reactant 2

HCID 7516PhenylhydrazineHCID 178468297HCID 178468297, compound

Product 1

HCID 86677496HCID 86677496, compound

Procedure

The product was obtained starting from (Z)-ethyl N-2-chloroacetyl-3-fluorobenzimidate (535 mg, 1.98 mmol) and phenylhydrazine (270 mg, 246 μL, 2.37 mmol) according to the method described in example 57, step 2 as orange solid (448 mg, 1.56 mmol, 78.8%).

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-c93ad936333f4233bd69952e54609f16
Source dataset
uspto-grants-2014_07
Patent number
US08772510B2

Reaction notes

Loading…