HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-methylbenzaldehyde → 6-fluoro-2-(4-methoxybenzyl)-7-methylisoquinolin-1(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-methylbenzaldehyde | HCID 2734874 | — |
| Reactant | 7-Chloro-6-fluoro-2-[(4-methoxyphenyl)methyl]isoquinolin-1(2H)-one | HCID 59818247 | — |
| Product | 6-fluoro-2-(4-methoxybenzyl)-7-methylisoquinolin-1(2H)-one | HCID 59226043 | — |
Reaction Steps
Starting from 3-methyl-4-fluoro benzaldehyde, the title compound was prepared following a similar sequence as described for 7-chloro-6-fluoro-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one (62). Rt=1.83 min (Method B). Detected mass: 298.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772492B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-e58da68ef1fd4a0fb34c5e99a53c6ce5 |
| Source note | uspto-grants-2014_07 |