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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1621510Generated: November 4, 2026

m-Chloroperbenzoic acid → N-(6-Methoxypyridin-3-YL)-3-(2-methyl-6-(methylsulfinyl)pyrimidin-4-YL)pyrazin-2-amine

https://huagongshe.com/reaction/1621510

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Chloroperbenzoic acidHCID 70297—
ReactantN-(6-methoxypyridin-3-yl)-3-(2-methyl-6-(methylthio)pyrimidin-4-yl)pyrazin-2-amineHCID 66599972—
Solvent1,4-DioxaneHCID 31275—
ProductN-(6-Methoxypyridin-3-YL)-3-(2-methyl-6-(methylsulfinyl)pyrimidin-4-YL)pyrazin-2-amineHCID 66600383—

Reaction Steps

A glass microwave reaction vessel was charged with N-(6-methoxypyridin-3-yl)-3-(2-methyl-6-(methylthio)pyrimidin-4-yl)pyrazin-2-amine (11 mg, 0.032 mmol) and 3-chloroperoxybenzoic acid (11.15 mg, 0.065 mmol) in dioxane (1 mL). The reaction mixture was stirred at room temperature for 1 h. The reaction mixture was used for the next step reaction without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772480B2
Source datasetuspto-grants-2014_07
ORD IDord-058a561592bf45d59d99ed44cce620d2
Source noteuspto-grants-2014_07