5-Fluoro-6-methoxypyridin-3-amine → HCID 59548162, compound

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Reaction Steps

The title compound was prepared in an analogous manner to that described in Example 254 using 4-(2-fluoro-6-(2-methoxyethoxy)pyridin-3-yl)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine and 5-fluoro-6-methoxypyridin-3-amine (Anichem), and was isolated as yellow amorphous powder (4.9%). m/z (ESI, +ve ion) 402.0 (M+H)+. 1H NMR (400 MHz, d4-MeOH) δ 12.15 (1H, br. s.); 8.77 (1H, d, J=8.6 Hz); 8.32 (1H, br. s.); 8.15 (1H, br. s.); 6.30 (1H, s); 3.98 (3H, s); 3.72 (2H, br. s.); 3.37 (4H, s); 2.44 (4H, s).

Provenance & Evidence