HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Dopamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dopamine Hydrochloride | HCID 65340 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | Phosphate Buffered Saline | HCID 24978514 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Dopamine | HCID 681 | 90% |
Reaction Steps
The CNT obtained in Manufacturing Example 2 was added to a solvent mixture of phosphate buffered saline (“PBS”) and acetone mixed in the ratio of 1:1 to have a concentration of 0.5 milligrams per milliliter (mg/ml) and then 1 M of hydrogen chloride (HCl) was used to adjust the acidity of the mixture to a pH of 5.5. Here, 147.5 mg of 1-ethyl-3-(dimethylaminopropyl)carbodiimide hydrochloride and 145.9 mg of dopamine hydrochloride were added to the mixture and mixed for about 4 hours. After completing the mixing, the resulting CNT was separated from the mixture using a 0.2 μm polycarbonate filter and then was dried, thereby obtaining a composite having a yield of 90 percent (%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778296B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-b308fa6570c94f91bc7c1ff82f00c9f4 |
| Source note | uspto-grants-2014_07 |