Isopropanol → HCID 67683009, compound

HRID 1622036Notes

Reaction equation

[F:1][C:2]1[CH:7]=[C:6]([CH2:8][C:9]([OH:11])=[O:10])[CH:5]=[CH:4][C:3]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[CH3:18][CH:19](O)[CH3:20]>>[F:1][C:2]1[CH:7]=[C:6]([CH2:8][C:9]([O:11][CH:19]([CH3:20])[CH3:18])=[O:10])[CH:5]=[CH:4][C:3]=1[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

Reactant 2

HCID 3776Isopropanol

HCID 118312372-(2-Fluoro-(1,1'-biphenyl)-4-yl)acetic acid

Product 1

HCID 67683009HCID 67683009, compound

Procedure

2-propyl (2-fluorobiphenyl-4-yl)acetate (20) was synthesized from 2-(2-fluorobiphenyl-4-yl)acetic acid and 2-propanol according to a similar procedure to step 1 of Example 15. The 1H NMR spectrum of this substance is shown below.

Sources & evidence

ORD record: ord-b63006cc13184465a6f57d59d86fb840
Source dataset: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08778298B2

Reaction notes

Loading…