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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1622106Generated: October 27, 2026

1-(Chloromethoxy)-2-methoxyethane → Methyl 2-(3-bromo-5-formyl-4-((2-methoxyethoxy)methoxy)phenyl)acetate

https://huagongshe.com/reaction/1622106

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Chloromethoxy)-2-methoxyethaneHCID 77590—
ReactantMethyl 2-(3-bromo-5-formyl-4-hydroxyphenyl)acetateHCID 57198039—
ProductMethyl 2-(3-bromo-5-formyl-4-((2-methoxyethoxy)methoxy)phenyl)acetateHCID 54469909—

Reaction Steps

Proceeding as in Reference 12, but substituting methyl 3-bromo-5-formyl-4-hydroxyphenylacetate (27.32 g, 0.10 mole) and 2-methoxyethoxymethyl chloride (0.125 mol, 14.3 mL), gave methyl 3-bromo-5-formyl-4-(2-methoxyethoxymethoxy)-phenylacetate (31.4 g (87%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778625B2
Source datasetuspto-grants-2014_07
ORD IDord-d984e27fb6b04950adc29ff2ac17f87c
Source noteuspto-grants-2014_07