Dimethylcarbamoyl Chloride → 2-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid dimethylamide

HRID 162257Notes

Reaction equation

HRID 162257 reaction equation
[CH3:31][N:32]([C:33](=[O:34])[Cl:35])[CH3:36].[Cl:1][c:2]1[n:3][c:4]([N:25]2[CH2:26][CH2:27][O:28][CH2:29][CH2:30]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][C:14]3([CH2:15]1)[CH2:16][CH2:17][N:18]([S:21]([CH3:22])(=[O:23])=[O:24])[CH2:19][CH2:20]3)[s:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:25]2[CH2:26][CH2:27][O:28][CH2:29][CH2:30]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][C:14]3([CH2:15]1)[CH2:16][CH2:17][N:18]([C:33]([N:32]([CH3:31])[CH3:36])=[O:34])[CH2:19][CH2:20]3)[s:10]2

Participants

3

Reactant 2

HCID 6598Dimethylcarbamoyl ChlorideHCID 581171302-Chloro-6-(7-methanesulfonyl-2,7-diaza-spiro[3.5]non-2-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

Product 1

HCID 581171092-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid dimethylamide

Sources & evidence

ORD record
ord-4d49d1f4fbad48039d6f3763c3432fb0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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