反应详情

A solution of Example 8D (2.2 g, 5.0 mmoles) was taken in ethanol (8 mL) and 12M HCl (1 mL) was added. The reaction was stirred at room temperature for twelve hours. The solvent was evaporated in vacuo and the residue was purified by flash column chromatography (hexanes; ethyl acetate 100:0 to 50:50) to obtain the titled compound as a mixture of diastereomers.

1. customThe solvent was evaporated in vacuo
2. customthe residue was purified by flash column chromatography (hexanes; ethyl acetate 100:0 to 50:50)