1,4-Dioxane hydrochloride → HCID 66616818, compound

Participants

Reaction Steps

Cyclopentyl N-(tert-butoxycarbonyl)-2-methylalaninate (0.254 g, 0.93 mmol) was dissolved in THF (5 ml) and treated with 4M HCl/dioxane (2 ml) and the reaction mixture was stirred at RT for 24 hours. The crude mixture was concentrated under reduced pressure and triturated with Et2O to give a white precipitate. This was further washed with Et2O to give the desired product as a white powder (0.16 g, 82% yield).

Provenance & Evidence