HCID 86052868, compound → HCID 86612248, compound

Participants

Reaction Steps

The general method of Part G of Example 6 was followed using 4-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)butyraldehyde O-methyloxime (17.5 g, 56.5 mmol), prepared as described in Parts A-D of Example 6, in lieu of N-methoxy-N-[4-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]acetamide. Purification by flash column chromatography on silica gel afforded 11.4 g of 4-(4-amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)butyraldehyde O-methyloxime.

Provenance & Evidence